Peer-reviewed veterinary case report
Hyperthyroid cats often have lung artery changes but rarely high lung
By Billings, Caroline et al.·Published in American journal of veterinary research·2023·Department of Veterinary Medicine and Surgery·View original on PubMed →
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Original publication title: Hyperthyroid cats have altered pulmonary arterial hemodynamics but rarely have intermediate or high probability of pulmonary hypertension.
- Species:
- cat
Plain-English summary
A group of 27 cats, including 16 with hyperthyroidism, were examined to see if they had pulmonary hypertension (PH), a condition that affects blood flow in the lungs. The study found that hyperthyroid cats showed some changes in heart function but did not consistently show signs of PH. Only two hyperthyroid cats had measurable signs that could indicate PH, one with a high probability and another with a low probability. Overall, while hyperthyroid cats had altered heart dynamics, they rarely had significant pulmonary hypertension.
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Abstract
OBJECTIVE: Apply the 3-site echocardiographic metrics utilized to assess pulmonary hypertension (PH) probability in dogs and humans to feline echocardiographic examinations to investigate the translatability of this scheme and subsequent enhancement of detection of PH in cats. ANIMALS: 27 client-owned cats (euthyroid [n = 11] and hyperthyroid [16]). METHODS: This was a single-center, prospective, observational case-control study. Demographic, physical examination, and echocardiographic data from hyperthyroid and euthyroid cats were compared via Fisher exact test and Kruskal-Wallis test. RESULTS: Hyperthyroid versus euthyroid cats had significantly greater right atrial area index values and were more likely to have late-peaking main pulmonary artery pulsed-wave flow profiles. Two hyperthyroid cats had measurable tricuspid regurgitation tracings (one with a high probability of PH and another with a low probability of PH). CLINICAL RELEVANCE: Hyperthyroid cats demonstrated altered pulmonary arterial hemodynamics and lacked consistent intermediate or high probability of PH. The 3-site echocardiographic metrics scheme is applicable for the evaluation of right-sided cardiac and pulmonary arterial hemodynamics in cats. Further research is needed to determine reference ranges in larger populations of healthy cats and those with high clinical suspicion for PH.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/37748759/