Peer-reviewed veterinary case report
Hypertrophic muscular dystrophy in a cat and new test using fixed
By Blunden, A S & Gower, S·Published in The Veterinary record·2011·Animal Health Trust, United Kingdom·View original on PubMed →
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Original publication title: Hypertrophic feline muscular dystrophy: diagnostic overview and a novel immunohistochemical diagnostic method using formalin-fixed tissue.
- Species:
- cat
Plain-English summary
A cat in the UK died unexpectedly after a routine vaccination, and a postmortem examination revealed a condition called hypertrophic feline muscular dystrophy (HFMD). This disease affected the cat's diaphragm and other muscles, leading to complications like partial lung collapse. The study discusses the findings and introduces a new method for diagnosing this condition using tissue samples. Unfortunately, the cat did not survive, highlighting the serious nature of HFMD.
People also search for: cat muscular dystrophy symptoms · why did my cat die after vaccination · cat lung problems after vaccination
Abstract
This paper describes a case of hypertrophic feline muscular dystrophy (HFMD) in the UK. The cat under investigation died unexpectedly following routine vaccination, and postmortem investigation revealed myopathy, particularly affecting the diaphragm as well as multiple skeletal muscles. The right lung lobes were also partially collapsed and this was considered secondary to the effect of the muscular dystrophy. Pathological and immunohistochemical findings are described, macroscopic and microscopic findings are compared with other recorded cases in the literature and a diagnostic overview of HFMD is given. Possible causes of death are also discussed and a novel immunohistochemical method of demonstrating dystrophin deficiency using formalin-fixed tissue is described.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/21558128/