Peer-reviewed veterinary case report
Dog with swollen joints and paralysis from kidney cancer spread
By Chiang, Yu-Ching et al.·Published in The Journal of veterinary medical science·2007·Department of Veterinary Medicine·View original on PubMed →
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Original publication title: Hypertrophic osteopathy associated with disseminated metastases of renal cell carcinoma in the dog: a case report.
- Species:
- dog
Plain-English summary
A 6-year-old mixed breed dog was brought in with swelling in the left wrist and weakness in his front legs, which worsened over a month to include swelling in both wrists and ankles, and eventually paralysis in all four legs. X-rays revealed serious bone damage and swelling in the bones of his legs. Sadly, due to his poor quality of life and a grim outlook, the dog was euthanized. A thorough examination afterward found that he had renal cell carcinoma (a type of kidney cancer) that had spread to his lungs and bones.
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Abstract
A 6-year-old, mixed breed, intact male dog showed signs of left carpal joint swelling and weakness of the forelimbs one month before presentation. The symptoms gradually progressed to bilateral carpal and tarsal joint swelling and tetraparalysis. There were a number of radiographically identified lytic-proliferative bone lesions noted on the axial skeleton. Hypertrophic osteopathy of the metacarpi and all distal long bones was also evident. Because of the deteriorating quality of life and guarded prognosis, the patient was euthanized and a complete necropsy was performed. Renal cell carcinoma, with metastasis to the lung, thoracic vertebrae, ribs, and the right adrenal gland, was diagnosed. To our knowledge, renal cell carcinoma with bone metastases and hypertrophic osteopathy has not been reported in dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17339768/