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Peer-reviewed veterinary case report

Dog with bone swelling and lung blastomycosis infection

By Brockus, Charles W. & Hathcock, John T.·Published in Veterinary Radiology·1988·View original on Crossref

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Original publication title: HYPERTROPHIC OSTEOPATHY ASSOCIATED WITH PULMONARY BLASTOMYCOSIS IN A DOG

Species:
dog

Plain-English summary

A 5-year-old male mixed-breed dog was brought in for a persistent cough and limping after being treated for a chronic cough the previous year. Despite initial tests showing no signs of a fungal infection, the dog's condition worsened, leading to further imaging that revealed masses in the lungs. A biopsy confirmed the presence of a fungus called Blastomyces dermatitidis, which was linked to his symptoms. The dog was treated with two antifungal medications, amphotericin B and ketoconazole, which led to improvement in his cough and some recovery from the bone changes associated with his condition after five months of treatment.

People also search for: dog cough and limping · mixed-breed dog fungal infection treatment · blastomycosis in dogs

Abstract

Hypertrophic osteopathy (HO) associated with pulmonary blastomycosis was diagnosed in a 5–year‐old male mixed‐breed dog. One year prior to referral, increased pulmonary opacity had been identified on radiographs made during an examination for a chronic cough. Although serologic tests for blastomycosis were negative, the dog was treated with oral ketoconozole on the basis of suspicious lesions seen on radiographs and clinical signs. Ten months after completing the ketoconozole therapy, the dog was presented for a persistent cough and lameness. Intrapulmonary masses and periosteat proliferation were observed radiographically. A biopsy of the pulmonary masses was done, and Blastomyces dermatitidis was identified. Amphotericin B and ketoconozole administration resulted in clinical improvement and partial resolution of the HO lesions five months after initiation of therapy.

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Original publication on Crossref: https://doi.org/10.1111/j.1740-8261.1988.tb01773.x