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Peer-reviewed veterinary case report

Hypoadrenocorticism and thyroid issues in related Leonbergers

By Smallwood, L J & Barsanti, J A·Published in Journal of the American Animal Hospital Association·1995·Department of Small Animal Medicine and Surgery, United States·View original on PubMed

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Original publication title: Hypoadrenocorticism in a family of leonbergers.

Species:
dog

Plain-English summary

A family of four leonbergers was diagnosed with hypoadrenocorticism, a condition where the adrenal glands don't produce enough hormones. Two of these dogs also showed low levels of thyroid hormone and symptoms of hypothyroidism, which can cause issues like lethargy and weight gain. This situation is similar to a condition seen in humans where multiple glands are affected. Treatment options for these conditions typically involve hormone replacement therapy, which can help manage the symptoms and improve the dogs' overall health.

People also search for: leonberger adrenal gland disease · dog thyroid problems · hypoadrenocorticism treatment in dogs

Abstract

Hypoadrenocorticism was diagnosed in four related leonbergers. Two of the four dogs also had low-resting serum thyroxine (T4) levels and signs consistent with hypothyroidism. The familial association of the affected dogs and the presence of coexisting thyroid dysfunction are similar to what is seen in human type II polyglandular autoimmune syndrome.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/7552661/