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Peer-reviewed veterinary case report

Hypoadrenocorticism in a family of leonbergers.

Journal:
Journal of the American Animal Hospital Association
Year:
1995
Authors:
Smallwood, L J & Barsanti, J A
Affiliation:
Department of Small Animal Medicine and Surgery · United States
Species:
dog

Abstract

Hypoadrenocorticism was diagnosed in four related leonbergers. Two of the four dogs also had low-resting serum thyroxine (T4) levels and signs consistent with hypothyroidism. The familial association of the affected dogs and the presence of coexisting thyroid dysfunction are similar to what is seen in human type II polyglandular autoimmune syndrome.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/7552661/