Peer-reviewed veterinary case report
Cat with bone marrow failure and low B12 improves with treatment
By Stanley, E L & Eatroff, A EĀ·Published in Australian veterinary journalĀ·2017Ā·Internal Medicine Department, United StatesĀ·View original on PubMed ā
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Original publication title: Hypocobalaminaemia as a cause of bone marrow failure and pancytopenia in a cat.
- Species:
- cat
Plain-English summary
A male Domestic Short-hair cat was brought in for chronic weight loss, tiredness, and not eating well. Blood tests showed low red and white blood cell counts, as well as low platelets, indicating bone marrow failure. The vet found that the cat had low vitamin B12 levels and treated it with vitamin B12 injections. After two months of treatment, the cat's blood counts returned to normal, showing that low vitamin B12 can lead to serious blood issues in cats.
People also search for: cat weight loss and lethargy Ā· cat low vitamin B12 treatment Ā· cat bone marrow failure symptoms
Abstract
CASE REPORT: A male Domestic Short-hair cat was presented for chronic weight loss, lethargy and hyporexia. Complete haematological examination revealed non-regenerative anaemia, neutropenia and thrombocytopenia, as well as Howell-Jolly bodies, anisocytosis, polychromasia and macrocytosis on blood smear evaluation. Histopathological evaluation of bone marrow biopsy disclosed hypocellularity consistent with bone marrow failure. Concurrent hypocobalaminaemia was identified and treated with parenteral cyanocobalamin supplementation. Other differential diagnoses for pancytopenia, including infectious, toxic, immune-mediated and neoplastic causes, were ruled out. CONCLUSION: The cat's erythrocyte, leucocyte and platelet counts normalised after 2 months of cyanocobalamin supplementation, suggesting that pancytopenia may be a rare manifestation of feline cobalamin deficiency.
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Search related cases āOriginal publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/28444757/