Peer-reviewed veterinary case report
Lethargic Labrador with low cortisol recovered on prednisolone
By Dunn, K J & Herrtage, M E·Published in The Journal of small animal practice·1998·Department of Clinical Veterinary Medicine, United Kingdom·View original on PubMed →
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Original publication title: Hypocortisolaemia in a Labrador retriever.
- Species:
- dog
Plain-English summary
A 4-year-old Labrador retriever was brought to the vet because he was very tired and couldn't keep up during exercise. After some tests, the vet found that his body wasn't producing enough cortisol, a hormone that helps manage stress and energy levels. The dog was treated with a medication called prednisolone, which is a type of glucocorticoid, and he fully recovered.
People also search for: dog lethargy treatment · Labrador cortisol deficiency · prednisolone for dogs
Abstract
A four-year-old Labrador retriever was presented with lethargy and exercise intolerance. Clinical examination was unremarkable. A subnormal cortisol response to adrenocorticotrophin hormone (ACTH) was demonstrated (plasma cortisol concentrations before and after administration of ACTH were both below the detection limit of the assay) but plasma aldosterone concentrations were within the normal range. Endogenous plasma ACTH concentrations were high, indicating primary adrenocortical disease. Following glucocorticoid supplementation at a replacement dose (prednisolone 0.1 mg/kg) the dog made a full clinical recovery.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/9513891/