Peer-reviewed veterinary case report
Dog with low blood proteins and widespread plasma cell cancer case
By Brown, Juliet E et al.·Published in Veterinary clinical pathology·2021·U-Vet Werribee Animal Hospital and Faculty of Veterinary and Agricultural Science, Australia·View original on PubMed →
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Original publication title: Hypoglobulinemia in a dog with disseminated plasma cell neoplasia: Case report and review of the diagnostic criteria.
- Species:
- dog
Plain-English summary
A 6-year-old male Rottweiler was brought to the vet due to weight loss, lack of appetite, lethargy, vomiting, and soft stools. Tests showed that he had a high number of abnormal plasma cells in his bone marrow, which indicated a serious condition called disseminated plasma cell neoplasia (a type of cancer). Additionally, he had low levels of certain proteins in his blood, known as hypoglobulinemia. Unfortunately, the specific treatment details and outcome for this case were not provided, but it highlights the importance of thorough testing when a dog shows these concerning symptoms.
People also search for: Rottweiler weight loss vomiting treatment · dog cancer symptoms · hypoglobulinemia in dogs · plasma cell neoplasia in dogs
Abstract
This is the first reported case of hypoglobulinemia in a dog with disseminated plasma cell neoplasia. A 6-year-old male intact Rottweiler was referred to the U-Vet Animal Hospital (Werribee, Vic, Australia) for weight loss, hyporexia, lethargy, vomiting, and soft stools. Examination of a buffy coat preparation and splenic and liver aspirates revealed a monomorphic population of plasmacytoid cells, and the same cells comprised approximately 90% of bone marrow samples submitted for cytologic and histologic evaluation. Biochemistry revealed a hypoglobulinemia, and the presence of an M-protein was not supported by serum and urine protein electrophoresis or serum immunofixation. Immunohistochemistry demonstrated strong nuclear labeling for MUM-1.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/33913178/