Peer-reviewed veterinary case report
Vanadium lowers blood sugar in diabetic dogs given alloxan
By Kim, Joo-Min et al.·Published in Journal of veterinary science·2006·Department of Internal Medicine, South Korea·View original on PubMed →
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Original publication title: Hypoglycemic effects of vanadium on alloxan monohydrate induced diabetic dogs.
- Species:
- rodent
Plain-English summary
A group of diabetic dogs were given a supplement called vanadium to see if it could help lower their blood sugar levels. The dogs had diabetes induced by a chemical and were divided into two groups: one group received vanadium while the other group did not. Over three weeks, the dogs that received vanadium showed significantly lower blood sugar and fructosamine levels, which indicates better blood sugar control. Additionally, their cholesterol levels were also lower compared to the control group. This suggests that vanadium may be beneficial for managing diabetes in dogs.
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Abstract
The hypoglycemic effects after oral administration of vanadium have been studied previously in many species such as rats, mice and even humans. However, there has been no prior report on the glucose lowering effect of vanadium on diabetic dogs. Therefore, the purpose of this study was to evaluate the hypoglycemic effects of oral vanadium on diabetic dogs. Diabetes mellitus in the dogs studied was induced by alloxan monohydrate intravenous injection. The dogs were divided into two groups, one was the diabetic control (DC) group (n = 4) and the other was the vanadium treated (DV) group (n = 6). Fresh water was supplied to the dogs in the DC group, but sodium metavanadate solution (0.1approximately 0.2 mg/ml) was given to the dogs in DV group from one week after the alloxan injection. The fasting glucose levels, fructosamine and serum chemistry profiles were compared between the two groups weekly for three weeks. The fasting blood glucose levels in DV group were significantly lower than those in the DC group (p < 0.01). Fructosamine levels in the DV group were also lower than those in the DC group (p < 0.05). The serum chemistry profiles were not significantly different in comparisons between the two groups. However, the cholesterol levels were significantly lower in the DV group compared to the DC group (p < 0.05). Our findings showed that oral vanadium administration had a hypoglycemic effect on chemically induced diabetic dogs.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17106233/