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Peer-reviewed veterinary case report

Hypolipemic effect of water extracts of Picrorrhiza kurroa in high fat diet treated mouse.

Journal:
Fitoterapia
Year:
2006
Authors:
Lee, Hyeung Sik et al.
Affiliation:
Department of Herbal Biotechnology · South Korea

Abstract

A hypolipemic effect of the water extract of Picrorrhiza kurroa (PR) was observed in a high fat diet feeding hyperlipemic mouse at doses of 50, 100 and 200 mg/kg, orally, once a day for 12 weeks. Liver weight, serum aspartate transferase (AST), alanine transferase (ALT), low density lipoprotein (LDL), triglyceride and total cholesterol levels were significantly reduced by the treatment. On the contrary, serum HDL level seems not affected by P. kurroa water extract.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/17056204/