Peer-reviewed veterinary case report
Low phosphate linked to anemia in diabetic and liver cats
By Adams, L G et al.·Published in Journal of veterinary internal medicine·1993·Department of Small Animal Clinical Sciences·View original on PubMed →
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Original publication title: Hypophosphatemia and hemolytic anemia associated with diabetes mellitus and hepatic lipidosis in cats.
- Species:
- cat
Plain-English summary
A group of cats with diabetes and one with liver disease were found to have low phosphorus levels (hypophosphatemia) and were experiencing a drop in red blood cells (hemolytic anemia). Within 24 to 48 hours of the low phosphorus being detected, their anemia worsened. Treatment with intravenous potassium phosphate helped correct the phosphorus levels in most of the cats, leading to recovery from anemia. It's important for cat owners to monitor phosphorus levels in cats at risk for this condition, as it can lead to serious health issues.
People also search for: cat diabetes treatment · low phosphorus in cats · cat hemolytic anemia symptoms · hypophosphatemia in cats treatment
Abstract
Hypophosphatemia associated with hemolytic anemia was diagnosed in five cats with diabetes mellitus and in one cat with idiopathic hepatic lipidosis. The hematocrit began decreasing within 24 to 48 hours after documented hypophosphatemia in each case. The anemia resolved in all five surviving cats. Because of the temporal relationship and lack of other detectable causes, hemolytic anemia was presumed to be caused by hypophosphatemia. There were increased Heinz bodies in three of six hypophosphatemic cats during episodes of hemolysis. Intravenous potassium phosphate administration corrected the hypophosphatemia in four of five cats. The effective dosages of intravenous phosphate ranged from 0.011 to 0.017 mmol of phosphate/kg/h for 6 to 12 hours. Hypocalcemia (5.4 to 8.7 mg/dL) occurred in four of five cats treated with intravenous phosphate; however, only one cat developed clinical signs attributable to hypocalcemia. Based on this retrospective study, we recommend monitoring serum phosphorus concentration every 6 to 12 hours in cats likely to become hypophosphatemic. Treatment of hypophosphatemia in cats is warranted because of the apparent increased susceptibility of cats to hypophosphatemia-induced hemolysis. Cats with severe hypophosphatemia (< or = 1.5 mg/dL) should be given oral or parenteral phosphate if contraindications do not exist.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8263844/