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Peer-reviewed veterinary case report

Hypoxia as pathogenic factor affecting the eye tissues: The selective apoptotic damage of the conjunctiva and anterior epithelium of the cornea.

Journal:
Doklady. Biochemistry and biophysics
Year:
2016
Authors:
Akberova, S I et al.
Affiliation:
Medical Center "Medkvadrat
Species:
rodent

Abstract

The effect of acute hypoxia on the occurrence of apoptosis in eye cells in rats placed in a pressure chamber was studied. Selective primary lesion of cells of the conjunctiva and the anterior corneal epithelium was found. A possible role of the simulated hypoxic conditions in the dry eye syndrome pathogenesis, which is accompanied by primary lesion of cells in the anterior eye surface tissues is discussed.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/27193721/