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Peer-reviewed veterinary case report

Iatrogenic hyperadrenocorticism, calcinosis cutis, and myocardial infarction in a dog treated for IMT.

Journal:
Journal of the American Animal Hospital Association
Year:
2012
Authors:
Hsu, Kimberly et al.
Affiliation:
Department of Small Animal Clinical Sciences · Canada
Species:
dog

Abstract

An 8 yr old male English bulldog receiving treatment for immune-mediated thrombocytopenia was diagnosed with calcinosis cutis 90 days after initiation of corticosteroid therapy. Twenty-four days later, the patient presented in a comatose state after collapsing and was euthanized. Postmortem examination revealed coronary arteriosclerosis and myocardial infarction leading to congestive heart failure. Calcinosis cutis and myocardial necrosis were most likely complications associated with administration of corticosteroids in this dog. Important implications regarding the classification of calcinosis cutis and the use of immunosuppressive doses of corticosteroids are discussed.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/22474044/