Peer-reviewed veterinary case report
Id3 knockout mice as a new model for sjogren's syndrome: only a T cell defect or more?
- Journal:
- Immunity
- Year:
- 2004
- Authors:
- Versnel, Marjan A
- Affiliation:
- Department Immunology · Netherlands
- Species:
- rodent
Abstract
Id3(-/-) mice were found to have autoantibodies, lymphocytic infiltrates in, and decreased secretion by exocrine glands. Similar symptoms are found in primary Sjogren's Syndrome. In this issue of Immunity, Li and colleagues suggest an important role for Id3 function in T cell development and Sjogren's Syndrome.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/15485622/