Peer-reviewed veterinary case report
Canine kobuvirus found in dogs with diarrhea in eastern China
By Wang, Yong et al.·Published in Archives of virology·2020·College of Animal Science and Technology, China·View original on PubMed →
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Original publication title: Identification and full-genome sequencing of canine kobuvirus in canine fecal samples collected from Anhui Province, eastern China.
- Species:
- dog
Plain-English summary
A group of dogs in Anhui Province, eastern China, was found to have diarrhea caused by a newly identified virus called canine kobuvirus (CaKoV). Out of 57 fecal samples tested, five were positive for this virus, which can lead to gastroenteritis. Notably, all of these dogs were also infected with canine parvovirus, a serious illness that can worsen their condition. This discovery emphasizes the importance of monitoring and preventing infections in dogs, especially in areas where these viruses are present.
People also search for: dog diarrhea causes · canine kobuvirus symptoms · parvovirus treatment in dogs
Abstract
Canine kobuvirus (CaKoV), a newly described virus, is the causative agent of gastroenteritis in dogs. In this study, 57 fecal samples from dogs with diarrhea in Anhui Province, eastern China, were collected. Among these, five samples were identified to be infected with CaKoV, by polymerase chain reaction targeting the CaKoV 3D gene. The five CaKoV strains were subjected to phylogenetic analysis. The sequences of VP1 from the five CaKoV strains were 93.6%-96.1% identical to each other and 91.75%-97.95% identical to other reported CaKoV VP1 sequences. In addition, the complete genome of one strain was successfully amplified and sequenced. The genome consisted of 8223 nucleotides and shared 94.6%-97.0% nucleotide and 93.1%-94.0% amino acid sequence identity with other CaKoV isolates. Phylogenetic analysis revealed that the CaKoV strain from Anhui Province was similar to other Chinese strains, and it was more closely related to feline and mouse kobuviruses than to sheep and bovine kobuviruses. Interestingly, all of the CaKoV-positive samples were coinfected with canine parvovirus. The finding of CaKoV infection in dogs with diarrhea and coinfection with canine parvovirus are a cause for concern and highlight the need for management and preventive measures.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/32776176/