Identification and genetic evolution of Muscovy duck parvovirus in Guangdong province.

Abstract

In this study, we analyzed 137 liver samples collected from deceased Muscovy ducks in Guangdong, China, between 2020 and 2023. The Muscovy duck parvovirus (MDPV) strain GD2407 was isolated from these samples, and its genome sequence was determined. The genome of MDVP strain GD2407 is 5067 nt in length, encoding both non-structural and structural proteins, and its genome sequence is 99.9% identical to that of strain GDZJ1901. Recombination analysis suggested that strain GD2407 originated from a recombination event between MDPV and goose parvovirus (GPV). Phylogenetic analysis showed that strain GD2407 is genetically closely related to strain GDZJ1901 but distinct from strain GD201911, which was prevalent before 2020. These findings suggest that the circulation of MDPV in this region may contribute to illness and mortality in ducks.