Peer-reviewed veterinary case report
Dog with beef allergy reacts to bovine serum albumin protein
By Ohmori, Keitaro et al.·Published in The Journal of veterinary medical science·2007·Department of Veterinary Internal Medicine, Japan·View original on PubMed →
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Original publication title: Identification of bovine serum albumin as an IgE-reactive beef component in a dog with food hypersensitivity against beef.
- Species:
- dog
Plain-English summary
A dog with food allergies was found to be sensitive to beef, specifically a protein called bovine serum albumin (BSA). Testing showed that the dog's immune system reacted strongly to this beef component, which was confirmed through blood tests and skin tests. When the dog's serum was mixed with BSA before testing, the allergic reaction was reduced, indicating that BSA was the cause of the food hypersensitivity. This information can help guide dietary changes to avoid beef and manage the dog's allergies effectively.
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Abstract
IgE-reactive beef components were examined by an immunoblot analysis using a serum from a dog with food hypersensitivity against beef. The immunoblot analysis revealed a distinct band at approximately 66 kDa and a faint band at approximately 50 kDa. The immunoblot analysis for serum IgE reactivity to bovine serum albumin (BSA) also revealed a positive band at 66 kDa. Serum IgE reactivity to the 66-kDa protein of beef was diminished by pre-incubating the serum sample with BSA. Furthermore, a positive reaction to BSA was detected in intradermal testing in the dog. These results clearly indicated that BSA was an IgE-reactive beef component in the dog with food hypersensitivity against beef.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/17827899/