Peer-reviewed veterinary case report
Identification of Western equine encephalitis virus structural proteins that confer protection after DNA vaccination.
- Journal:
- Clinical and vaccine immunology : CVI
- Year:
- 2010
- Authors:
- Gauci, Penelope J et al.
- Affiliation:
- Biological Countermeasures · Australia
- Species:
- horse
Abstract
DNA vaccines encoding different portions of the structural proteins of western equine encephalitis virus were tested for the efficacy of their protection in a 100% lethal mouse model of the virus. The 6K-E1 structural protein encoded by the DNA vaccine conferred complete protection against challenge with the homologous strain and limited protection against challenge with a heterologous strain.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/19923571/