Peer-reviewed veterinary case report
Dog with eyelid and skin granulomas treated with L-asparaginase
By Collins, B K et al.·Published in Journal of the American Veterinary Medical Association·1992·Department of Surgical Sciences·View original on PubMed →
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Original publication title: Idiopathic granulomatous disease with ocular adnexal and cutaneous involvement in a dog.
- Species:
- dog
Plain-English summary
A 5-year-old male dog developed swollen eyelids and masses around his eyes, along with similar growths on his legs and other areas. Despite trying corticosteroids, the masses kept coming back. However, when treated with a specific medication called polyethylene glycol modified L-asparaginase, some of the masses shrank quickly. Unfortunately, the treatment's effectiveness was hard to measure because the dog sometimes improved on his own and there were issues with following the treatment plan.
People also search for: dog eyelid masses treatment · granulomatous disease in dogs · dog skin growths treatment
Abstract
Idiopathic granulomatous disease was the cause of bilateral eyelid masses and additional ocular adnexal disease in a dog. Histologically similar granulomas developed concurrently in distant sites including the limbs, prepuce, and testicles. Periodic resolution and redevelopment of the masses were observed and were unaffected by corticosteroid treatments. Rapid diminution of some of the masses was found after treatment with polyethylene glycol modified L-asparaginase, but poor client compliance and episodes of spontaneous resolution of some of the masses made it difficult to accurately assess effectiveness of treatment. Clinicians should be aware that ocular adnexal granulomas may simulate neoplasms and be a component of a more widespread disease process.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/1500332/