Peer-reviewed veterinary case report
Idiopathic hypereosinophilic syndrome causing high eosinophils in 3
By Sykes, J E et al.·Published in Journal of veterinary internal medicine·2001·Department of Small Animal Clinical Sciences, United States·View original on PubMed →
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Original publication title: Idiopathic hypereosinophilic syndrome in 3 Rottweilers.
Plain-English summary
Three Rottweilers were brought to the vet with high levels of eosinophils, a type of white blood cell, which can indicate an allergic reaction or other health issues. They showed signs of inflammation in their liver, spleen, lungs, and bone marrow, but the vets couldn't find a specific cause for this condition, known as idiopathic hypereosinophilic syndrome (IHES). Tests showed that their immunoglobulin E levels were very high, which often relates to allergies. Unfortunately, the dogs' condition was complex, and while they received care, the exact treatment outcome wasn't detailed.
People also search for: Rottweiler eosinophilia symptoms · dog liver inflammation treatment · high IgE levels in dogs
Abstract
Three Rottweilers with marked peripheral eosinophilia and infiltration of the liver, spleen, lungs, and bone marrow with eosinophils were diagnosed with idiopathic hypereosinophilic syndrome (IHES). Mean serum immunoglobulin E concentrations were markedly high. On cytogenetic analysis, no evidence of karyotypic abnormalities was found in bone marrow aspirates. Despite an extensive search, no underlying cause for the eosinophilia could be identified. In this study, cytogenetic analysis and measurement of serum IgE concentrations were used to differentiate IHES and eosinophilic leukemia.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/11300601/