Peer-reviewed veterinary case report
Idiopathic inflammatory bowel disease in dogs and cats: 84 cases (1987-1990).
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 1992
- Authors:
- Jergens, A E et al.
- Affiliation:
- Department of Veterinary Clinical Sciences
Plain-English summary
In a study involving 58 dogs and 26 cats diagnosed with idiopathic inflammatory bowel disease (a condition causing inflammation in the intestines without a known cause), many pets showed signs of ongoing stomach issues, such as watery diarrhea, vomiting, and not eating well, which led to weight loss. These pets often did not respond to dietary changes, and tests revealed various nonspecific abnormalities in their blood and other areas. When doctors examined tissue samples from the intestines, they found signs of damage like redness, fragility, and ulcers. The inflammation was mostly moderate and affected the stomach, small intestine, and colon. Overall, the study confirmed that inflammatory bowel disease is a common cause of chronic stomach problems in dogs and cats.
Abstract
Idiopathic inflammatory bowel disease was the diagnosis for 58 dogs and 26 cats, with signs of persistent gastroenteritis, failed responses to dietary trials, and histologic evidence of cellular infiltrates unrelated to other causes of gastrointestinal tract inflammation. Clinical signs of large intestinal dysfunction, watery diarrhea, vomiting, and anorexia with weight loss were common. Nonspecific hematologic, biochemical, and radiographic abnormalities frequently were observed. Mucosal biopsy specimens, obtained endoscopically, were histologically evaluated for severity of mucosal epithelial damage. Mucosal erythema, friability, enhanced granularity, and ulceration or erosion were the predominant endoscopic lesions. Inflammatory bowel disease lesions of moderate severity predominated in the stomach, duodenum, and colon. Lymphocytic/plasmacytic infiltrates were limited to the lamina propria in biopsy specimens from all regions of the gastrointestinal tract. Inflammatory bowel disease commonly is associated with chronic gastroenteritis in dogs and cats.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/1289345/