Peer-reviewed veterinary case report
Sclerosing orbital pseudotumor causing eye swelling in seven cats
By Billson, F Mark et al.·Published in Veterinary ophthalmology·2006·Department of Veterinary Clinical Studies, United Kingdom·View original on PubMed →
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Original publication title: Idiopathic sclerosing orbital pseudotumor in seven cats.
- Species:
- cat
Plain-English summary
Seven cats were diagnosed with a serious condition affecting their eyes, known as idiopathic sclerosing orbital pseudotumor, which caused swelling and pain around the eyes. Most of these cats showed symptoms that worsened over weeks to months, leading to issues in one eye that often spread to the other. Unfortunately, despite treatment attempts, six of the cats had to be euthanized due to the progression of the disease and associated pain. The condition involved significant fibrosis, meaning the normal tissue around the eyes became replaced with thick, fibrous tissue. The prognosis for affected cats is generally poor, but earlier diagnosis and more aggressive treatment could help improve outcomes in the future.
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Abstract
OBJECTIVE: To review the clinical presentation and histopathologic findings on a series of cats with orbital fibrotic disease and compare the data to that of humans with sclerosing orbital pseudotumor. ANIMALS: A retrospective study was undertaken, which identified tissue samples from seven cats between 1997 and 2002 with a history of orbital mass effect and pathology characterized by fibrous tissue proliferation. PROCEDURE: Information was obtained from medical records for affected cats, including age, sex, clinical signs, management, and outcome, with histopathology re-examined. RESULTS: Six of seven cats presented with unilateral orbital involvement that progressed to bilateral orbital disease despite treatment. Onset was insidious, evolving over weeks to months and was associated with fixation of orbital structures. Owners of six of the cats opted for euthanasia because of disease progression and pain. Histopathology of affected orbital tissue included extensive fibrosis with encapsulation of normal tissues without characteristics of neoplasia. CONCLUSIONS: Clinical findings and histopathology of globes and orbital tissues in cats bore many similarities to idiopathic sclerosing orbital pseudotumor in humans. In cats, the prognosis for the globe appears to be poor but an elucidation of the pathogenesis and earlier diagnosis coupled with more aggressive treatment modalities as indicated in humans may be beneficial.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16409245/