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Peer-reviewed veterinary case report

Dog itching from Japanese cedar pollen allergy linked to Cry j 3

By Kubota, Shota et al.·Published in Veterinary immunology and immunopathology·2012·Department of Veterinary Microbiology, Japan·View original on PubMed

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Original publication title: IgE reactivity to a Cry j 3, an allergen of Japanese cedar (Cryptomeria japonica) pollen in dogs with canine atopic dermatitis.

Species:
dog

Plain-English summary

A group of 15 dogs with atopic dermatitis (a skin condition caused by allergies) were tested for their sensitivity to a specific pollen allergen from Japanese cedar trees. The tests showed that all the dogs had an immune response to the allergen, with a significant number reacting to a particular component called Cry j 3. This suggests that Cry j 3 could be an important trigger for skin allergies in dogs. Understanding this can help veterinarians better diagnose and treat allergic reactions in affected pets.

People also search for: dog skin allergies treatment · why is my dog itching · atopic dermatitis in dogs · cedar pollen allergy in dogs

Abstract

The present study investigated IgE reactivity to a new Cryptomeria japonica pollen allergen (Cry j 3) in dogs with atopic dermatitis by using a fluorometric ELISA. Serum samples from 15 dogs that showed IgE sensitivity to crude C. japonica pollen allergen by ELISA were tested for specific IgE to each allergen, individually. All 15 dogs had anti-Cry j 1 IgE, 6 (40%) had anti-Cry j 2 IgE, and 11 (73%) had anti-Cry j 3 IgE. Further, we found that these anti-Cry j 3 IgE reacted to Cry j 3 with immunoblotting analysis. These findings indicate that Cry j 3 may be a major allergen in dogs.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/22749702/