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Peer-reviewed veterinary case report

Fibrodysplasia ossificans progressiva causing stiffness in a young cat

By Klang, Andrea et al.·Published in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·2013·Department of Pathobiology·View original on PubMed

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Original publication title: Imaging diagnosis: fibrodysplasia ossificans progressiva in a cat.

Species:
cat

Plain-English summary

A 1-year-old female cat was brought in because she was losing hair, having trouble walking, and seemed stiff. X-rays showed unusual hard lumps in her neck, back, shoulders, and legs. After further imaging, the vet diagnosed her with fibrodysplasia ossificans progressiva, a rare condition where soft tissues turn into bone. Unfortunately, this condition is not well understood and can lead to serious mobility issues.

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Abstract

A 1-year-old female cat was presented for progressive alopecia, gait abnormalities, and stiffness. Radiography demonstrated multiple calcified lesions within the soft tissues of the cervical and thoracic spine, shoulder, and limbs. Postmortem computed tomography provided more detailed information on the distribution, pattern, and extension of lesions. In addition, computed tomography helped guide sample selection for histopathology. The final diagnosis was fibrodysplasia ossificans progressiva. This is a rare disorder of unknown etiology, characterized by fibrosis and heterotopic bone formation in connective tissues. To the authors' knowledge, this is the first report describing this disease in a European cat.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/23578335/