Peer-reviewed veterinary case report
Imaging diagnosis--lack of contrast enhancement in metastatic cerebral adenocarcinoma.
- Journal:
- Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
- Year:
- 2012
- Authors:
- Singh, Jeannine Brunner et al.
- Affiliation:
- Vesuisse Faculty Bern
- Species:
- dog
Abstract
A 7-year-old female spayed Scottish Terrier was presented with central nervous system symptoms suggestive of a lesion in the forebrain. Magnetic resonance (MR) imaging revealed multifocal disease in the forebrain. Because of complete lack of contrast enhancement, the changes were attributed to lesions of inflammatory origin. Histopathology of the brain revealed multiple metastatic lesions of an adenocarcinoma. Brain metastases in general show contrast enhancement. The reason for a complete absence of contrast enhancement is unknown. Previous administration of corticosteroids, increased diffusion time of contrast medium, increased intracranial pressure in combination with an intact blood-tumor barrier is discussed as possible reasons.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/22734151/