Peer-reviewed veterinary case report
Imaging diagnosis--Neuronal ceroid lipofuscinosis with a chronic subdural hematoma.
- Journal:
- Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association
- Year:
- 2010
- Authors:
- Asakawa, Midori Goto et al.
- Affiliation:
- Department of Population Health and Pathobiology · United States
- Species:
- dog
Abstract
A subdural hematoma was found to accompany neuronal ceroid lipofuscinosis in an 11-month-old Dachshund. Results from clinical, magnetic resonance (MR) imaging, histopathologic, ultrastructural, and molecular assessments are described. The dog had a 3-month history of progressive neurologic signs. In MR images, there was severe asymmetric cerebral atrophy with a subdural hematoma. Histopathologically, there was autofluorescent, periodic acid-Schiff-positive lipopigment in neurons and transmission electron microscopy confirmed a typical curvilinear profile of the storage bodies. We hypothesize that rapid brain atrophy contributed to the subdural hematoma formation, a complication not described previously in dogs with neuronal lipofuscinosis.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/20402401/