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Peer-reviewed veterinary case report

Dachshund with brain shrinkage and chronic subdural hematoma

By Asakawa, Midori Goto et al.·Published in Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association·2010·Department of Population Health and Pathobiology, United States·View original on PubMed

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Original publication title: Imaging diagnosis--Neuronal ceroid lipofuscinosis with a chronic subdural hematoma.

Species:
dog
Brain & nervesDogs

Plain-English summary

An 11-month-old Dachshund was brought in after showing worsening neurological symptoms for three months. Imaging revealed a subdural hematoma, which is a collection of blood outside the brain, along with severe brain shrinkage. The dog's condition was linked to neuronal ceroid lipofuscinosis, a genetic disorder that affects brain cells. Unfortunately, this combination of issues is rare and complicated, and the specific treatment outcomes were not detailed.

People also search for: Dachshund neurological symptoms · dog subdural hematoma treatment · neuronal ceroid lipofuscinosis in dogs

Abstract

A subdural hematoma was found to accompany neuronal ceroid lipofuscinosis in an 11-month-old Dachshund. Results from clinical, magnetic resonance (MR) imaging, histopathologic, ultrastructural, and molecular assessments are described. The dog had a 3-month history of progressive neurologic signs. In MR images, there was severe asymmetric cerebral atrophy with a subdural hematoma. Histopathologically, there was autofluorescent, periodic acid-Schiff-positive lipopigment in neurons and transmission electron microscopy confirmed a typical curvilinear profile of the storage bodies. We hypothesize that rapid brain atrophy contributed to the subdural hematoma formation, a complication not described previously in dogs with neuronal lipofuscinosis.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/20402401/