Peer-reviewed veterinary case report
Immune cell heterogeneity in a mouse model of diabetic kidney disease.
- Journal:
- Kidney international
- Year:
- 2022
- Authors:
- Wu, Haojia & Humphreys, Benjamin D
- Affiliation:
- Department of Medicine · United States
Abstract
Typical kidney single-cell RNA-sequencing contains relatively few leukocytes, complicating efforts to understand how immune cells impact kidney disease progression. In this issue, Fu et al. use a flow sorting strategy to generate a very large immune cell single-cell RNA-sequencing atlas in a mouse model of diabetic kidney disease. These findings highlight the importance of leukocyte cell subtypes in diabetic kidney disease.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/36411016/