Peer-reviewed veterinary case report
Immune-mediated hemolytic anemia in a horse.
- Journal:
- Journal of the American Veterinary Medical Association
- Year:
- 1991
- Authors:
- Messer, N T & Arnold, K
- Affiliation:
- Department of Clinical Sciences · United States
- Species:
- horse
Plain-English summary
An 18-year-old Quarter Horse gelding was diagnosed with immune-mediated hemolytic anemia, which means his immune system was mistakenly attacking his own red blood cells. This was confirmed through tests that showed clumping of the red blood cells and a positive result on a specific test called the direct Coombs test. Initially, treatment with corticosteroids didn't help, so the veterinarians switched to stronger medications called cyclophosphamide and azathioprine. After using these chemotherapeutic drugs, the horse's anemia improved.
Abstract
An 18-year-old Quarter Horse gelding was determined to have immune-mediated hemolytic anemia after detection of autoagglutination of RBC spherocytosis as well as a positive direct Coombs test result. A lack of response to treatment with corticosteroids necessiated the administration of cyclophosphamide and azathioprine. The anemia resolved after treatment with chemotherapeutic drugs.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/2061160/