Peer-reviewed veterinary case report
Immune Tolerance, Xenografts, and Large-Animal Studies in Transplantation.
- Journal:
- Annals of the American Thoracic Society
- Year:
- 2017
- Authors:
- Sachs, David H
- Affiliation:
- Department of Surgery · United States
Abstract
This article summarizes studies in which the author has been involved over several decades, directed toward providing solutions for the three major limitations to the field of transplantation: (1) drug treatment-related complications; (2) chronic rejection; and (3) the availability of transplantable organs. The first two of these limitations may be overcome by induction of transplantation tolerance, while the third will also require a new source of organs, for which great strides are now being made in xenotransplantation through genetic engineering.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/28945472/