Peer-reviewed veterinary case report
Bone marrow metastases confirmed in Bernese mountain dog with liver
By Mischke, R et al.·Published in The Journal of small animal practice·2003·Clinic for Small Animals, Germany·View original on PubMed →
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Original publication title: Immunocytological confirmation of bone marrow metastases in a dog with cholangiocarcinoma.
- Species:
- dog
Plain-English summary
A 4-year-old male Bernese mountain dog was diagnosed with cholangiocarcinoma, a type of cancer that started in the liver and spread to the bone marrow. The dog showed signs of illness, and tests revealed cancer cells in both the liver and bone marrow. Unfortunately, due to the severe prognosis, the dog was euthanized. This case highlights the importance of checking for cancer spread in pets, especially when liver tumors are present.
People also search for: dog liver cancer symptoms · Bernese mountain dog cancer treatment · bone marrow metastases in dogs
Abstract
The case history of a four-year-old, male Bernese mountain dog is presented. Carcinoma cells were detected in the liver by ultrasound-guided fine-needle aspiration. Bone marrow aspirated from the iliac crest and the left femur showed a distinct infiltration by carcinoma cells. Immunocytological examination of the liver and bone marrow metastases showed a negative staining result for large spectrum cytokeratin (CK) KL1, a strong positive result for CK7 and a focal weak positive result for CK20. The dog was euthanased due to the grave prognosis. Histopathological examination revealed metastatic cholangiocarcinoma. The authors conclude that cytological and immunocytological examination of bone marrow aspirates should be used more frequently for the detection of distant metastases of carcinomas in small animal medicine.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/14510332/