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Peer-reviewed veterinary case report

Dog with multiple myeloma and two types of abnormal antibodies

By Peterson, E N & Meininger, A C·Published in Journal of the American Animal Hospital Association·1997·Rowley Memorial Animal Hospital, United States·View original on PubMed

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Original publication title: Immunoglobulin A and immunoglobulin G biclonal gammopathy in a dog with multiple myeloma.

Species:
dog

Plain-English summary

A 9-year-old golden retriever was brought in for chronic loss of appetite, vomiting, and diarrhea. The vet found that the dog had lost weight, had pale gums, and had an enlarged liver and spleen. Tests revealed anemia and high levels of certain proteins, along with infections from parasites. Unfortunately, the dog was diagnosed with multiple myeloma, a type of cancer affecting blood cells, and the owner chose to euthanize the dog to prevent further suffering.

People also search for: dog vomiting and diarrhea · golden retriever weight loss · multiple myeloma in dogs · dog cancer symptoms · dog euthanasia decision

Abstract

A nine-year-old golden retriever was referred for evaluation of chronic anorexia, vomiting, and diarrhea. Low body weight, mucous membrane pallor, and palpably enlarged liver and spleen were detected by physical examination. Anemia, hyperglobulinemia, and concurrent trichuriasis and coccidiosis were identified upon initial diagnostic evaluation. Punctate vertebral lysis was apparent radiographically. Atypical plasma cell proliferation was found in the bone marrow, liver, and spleen. An immunoglobulin A and immunoglobulin G biclonal gammopathy was demonstrated by serum protein electrophoresis and immunoelectrophoresis. The dog was diagnosed with multiple myeloma and euthanized per owner request. Multiple myeloma should be considered in the differential diagnosis for biclonal gammopathy in the dog.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/8974026/