Peer-reviewed veterinary case report
Immunohistochemical and histopathological characteristics of adenomas and adenocarcinomas of Meibomian glands in dogs.
- Journal:
- Folia histochemica et cytobiologica
- Year:
- 2025
- Authors:
- Ciaputa, Rafal et al.
- Affiliation:
- Wroclaw University of Environmental and Life Sciences
- Species:
- dog
Abstract
INTRODUCTION: This study aimed to provide a comprehensive histopathological and immunohistochemical analysis of Meibomian adenomas and adenocarcinomas. MATERIAL AND METHODS: A total of 80 tumours were included in the study: 33 adenomas and 47 Meibomian adenocarcinomas. Ki-67, cytokeratin-7 and von Willebrand factor antibodies were used for the immunohistochemical staining. RESULTS: Detailed characteristics of inflammatory infiltration depending on tumor type and damage to surrounding tissue by tumour cells are presented. A close correlation was found between the structure and intensity of blood vessel proliferation and the level of factor VIII expression. CONCLUSIONS: The presented detailed histopathological analysis, combined with the results of immunohistochemical studies, now allows for better treatment planning and prognosis assessment for patients.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/41084773/