Peer-reviewed veterinary case report
Dogs with soy allergy tested for reactions to hydrolyzed soy protein
By Puigdemont, Anna et al.·Published in American journal of veterinary research·2006·Department de Farmacologia, Spain·View original on PubMed →
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Original publication title: Immunologic responses against hydrolyzed soy protein in dogs with experimentally induced soy hypersensitivity.
- Species:
- dog
Plain-English summary
Nine Beagle puppies with soy allergies were tested to see how they reacted to hydrolyzed soy protein, a form of soy that has been broken down to make it less likely to cause allergic reactions. After being sensitized to soy, these dogs showed high levels of soy-specific antibodies and had allergic reactions when given regular soy protein. However, when they were given hydrolyzed soy protein, they had much less inflammation and no symptoms at all. This suggests that hydrolyzed soy protein could be a safe option for dogs with food allergies, allowing them to eat without having allergic reactions.
People also search for: dog soy allergy symptoms · hypoallergenic dog food · Beagle food allergies treatment
Abstract
OBJECTIVE: To assess whether dogs with experimentally induced type I hypersensitivity against soy protein would respond to soy hydrolysate and develop cutaneous or gastrointestinal tract reactions after intradermal and oral challenge exposure. ANIMALS: 12 naïve Beagle pups (9 sensitized and 3 control dogs). PROCEDURE: 9 dogs were sensitized against soy protein by administration of allergens during a 90-day period. After the sensitization period, serum concentrations of soy-specific IgE were determined and an intradermal test was performed to confirm the dogs were sensitized against soy protein. An intradermal challenge test and an oral challenge test with native and hydrolyzed soy protein were conducted on 6 sensitized and 2 control dogs. RESULTS: High serum concentrations of soy-specific IgE and positive results for the intradermal test were observed for the 9 sensitized dogs after completion of the sesitization process. Sensitized dogs challenge exposed with hydrolyzed soy protein had a reduced inflammatory response after intradermal injection and no clinical response after an oral challenge exposure, compared with responses after intradermal and oral challenge exposure with native soy protein. CONCLUSIONS AND CLINICAL RELEVANCE: Soy-sensitized dogs did not respond to oral administration of hydrolyzed soy protein. Thus, hydrolyzed soy protein may be useful in diets formulated for the management of dogs with adverse reactions to food.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/16506912/