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Peer-reviewed veterinary case report

Immune test results in 3 dogs with allergic rhinitis from dust mites

By Kurata, Keigo et al.·Published in The Journal of veterinary medical science·2004·Department of Veterinary Internal Medicine, Japan·View original on PubMed

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Original publication title: Immunological findings in 3 dogs clinically diagnosed with allergic rhinitis.

Species:
dog

Plain-English summary

Three dogs diagnosed with allergic rhinitis (a condition causing sneezing and nasal irritation) were tested to find out what was causing their symptoms. The tests showed that they were allergic to house dust mites, which are common allergens. Their immune response was stronger compared to healthy dogs, indicating that their bodies were reacting more aggressively to the dust mites. This suggests that the dogs' allergic reactions were linked to a specific immune response type. Treatment options for allergic rhinitis may include allergy medications or immunotherapy to help manage their symptoms.

People also search for: dog sneezing treatment · allergic rhinitis in dogs · house dust mite allergy in dogs

Abstract

Three dogs clinically diagnosed with allergic rhinitis (AR) were examined for their immunological findings. House dust mites (HDM) such as Dermatophagoides farinae (DF) and D. pteronyssinus (DP) were identified as positive allergens in the 3 dogs with both intradermal skin test and serum antigen-specific IgE test. Lymphocyte blastogenic response of peripheral blood mononuclear cells (PBMCs) under stimulation with DF antigen in dogs with AR was higher than that in 4 healthy control dogs. Expression level of IL-4 mRNA in PBMCs obtained from the 3 AR dogs was higher than that in PBMCs obtained from 4 healthy control dogs before and after stimulation with DF antigen. Expression level of IFN-gamma mRNA in PBMCs was not different between the AR and control dogs before and after stimulation with DF antigen. These results suggested that allergic reaction to HDM antigen and T(H)2-type immune response were associated with the development of AR in 3 dogs examined in this study.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/14960806/