Peer-reviewed veterinary case report
Immunophenotypic characterization of canine malignant lymphoma: a retrospective study of cases diagnosed in Poland Lower Silesia, over the period 2011-2013.
- Journal:
- Veterinary and comparative oncology
- Year:
- 2016
- Authors:
- Pawlak, A et al.
- Affiliation:
- Department of Biochemistry
- Species:
- dog
Abstract
Lymphoma is the most frequently diagnosed cancer of the canine haematopoietic system. In this study, the flow cytometry and polymerase chain reaction (PCR) analysis were used to characterize a series of canine lymphomas in detail. The aim of this study was to determine the incidence of B- and T-cell high-grade lymphomas and their immunophenotypic characterization in Lower Silesia, Poland. The results show that the frequency of each type of lymphoma is 71% for B-cell and 17% for T-cell lymphomas. In two cases the PCR techniques confirmed the presence of simultaneous double gene rearrangements of the BCR and TCR receptors.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/25052381/