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Peer-reviewed veterinary case report

Immunosuppressive influence of Anguillid herpesvirus-1 (AngHV-1) infection on cellular defense mechanisms in European eel (Anguilla anguilla).

Journal:
Polish journal of veterinary sciences
Year:
2019
Authors:
Schulz, P et al.
Affiliation:
Department of Microbiology and Clinical Immunology

Abstract

The European eel (Anguilla anguilla) is a catadromous fish with a complicated life cycle. The long-term impact of anthropopressure, environmental pollution and diseases have led to a risk of extinction. The aim of the present study was to determine the influence of Anguillid herpesvirus-1 infection on the innate immunity of European eel from natural conditions. Spleen phagocyte respiratory burst activity and potential killing activity, as well as pronephros lymphocyte proliferation stimulated by concanavalin A or lipopolysaccharide were measured. The analyses of the results showed that all studied parameters were significantly higher (P⟨0.05) in AngHV-1-negative fish compared to the ones where the presence of viral DNA was confirmed.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/31867926/