Peer-reviewed veterinary case report
Impact of Candida auris Infection in a Neutropenic Murine Model.
- Journal:
- Antimicrobial agents and chemotherapy
- Year:
- 2020
- Authors:
- Torres, Steven R et al.
- Affiliation:
- Department of Biomedical Sciences · United States
Abstract
has become a global public health threat due to its multidrug resistance and persistence. Currently, there are limited murine models to studyinfection. Those models use a combination of cyclophosphamide and cortisone acetate, suppressing both innate and adaptive immunity. Here, we compareinfection in two neutrophil-depleted murine models in which innate immunity is targeted using the monoclonal antibodies 1A8 and RB6-8C5.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/31818824/