Peer-reviewed veterinary case report
Using near-infrared imaging to improve lung tumor surgery in dogs
By Sakurai, Naoki et al.·Published in Frontiers in veterinary science·2023·Department of Veterinary Medicine, Japan·View original on PubMed →
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Original publication title: Impact of near-infrared fluorescence imaging with indocyanine green on the surgical treatment of pulmonary masses in dogs.
- Species:
- dog
Plain-English summary
A group of 40 dogs with lung tumors underwent surgery to remove the masses, and a special imaging technique using indocyanine green (ICG) was used to help identify the tumors and check for cancer spread to lymph nodes. The imaging showed all tumors during surgery, and it was particularly effective in detecting cancer in lymph nodes. However, it was less reliable in confirming that all of the tumor was completely removed. Overall, the ICG imaging could be a helpful tool for veterinarians during lung surgery in dogs with cancer.
People also search for: dog lung tumor treatment · indocyanine green imaging for dogs · dog cancer surgery outcomes
Abstract
OBJECTIVES: To investigate the intraoperative identification and complete resection of pulmonary masses, and to evaluate lymph node metastasis of pulmonary malignant tumors in dogs using indocyanine green (ICG) fluorescence imaging. METHODS: Forty dogs with pulmonary masses were included, all of which underwent surgical treatment. ICG fluorescence imaging was performed on pulmonary masses before lobectomy and the resection margins after lobectomy. In addition, ICG fluorescence of the excised masses and lymph nodes was evaluated in the shaded box. The fluorescence findings were compared with the histopathological diagnosis. RESULTS: Of 44 nodules resected from 40 dogs, 32 nodules were histopathologically diagnosed as lung adenocarcinoma, five were histiocytic sarcoma, three were undifferentiated sarcoma, two were malignant epithelial tumor metastases, one was carcinosarcoma, and one was a non-neoplastic lesion. Fluorescence was observed in all nodules. In addition to the main lesion, other fluorescent nodules were found in four dogs. Regarding the diagnostic accuracy of complete resection based on ICG fluorescence, the sensitivity was 67.7% and the specificity was 60.0%. The sensitivity and specificity of ICG fluorescence for the diagnosis of lymph node metastasis were 100 and 75.0%, respectively. CONCLUSIONS: ICG fluorescence imaging might be a useful intraoperative diagnostic method to identify the location of tumors and lymph node metastasis, but not to evaluate complete tumor resection, in dogs with pulmonary malignant tumors.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/36825232/