Peer-reviewed veterinary case report
Implementation of internal laboratory quality control procedures for the monitoring of ELISA performance at a regional veterinary laboratory.
- Journal:
- Veterinary microbiology
- Year:
- 1996
- Authors:
- Blacksell, S D et al.
- Affiliation:
- CSIRO Australian Animal Health Laboratory · Australia
Plain-English summary
A veterinary laboratory in northern Thailand set up new quality control procedures to improve the accuracy of tests for hog cholera virus and foot and mouth disease virus. They used a computer program called QCEL to help manage and analyze the quality control data. This program created charts to track any unusual changes in test results over time. By using this system, the laboratory was able to feel more confident in the reliability of their test results. Overall, the implementation of these quality control measures was successful in enhancing test performance.
Abstract
Quality control (QC) procedures for antigen detection enzyme-linked immunosorbent assays (ELISAs) for hog cholera (HC) virus, foot and mouth disease (FMD) virus, and an antibody detection ELISA for FMD virus were established at a regional veterinary laboratory in northern Thailand. A recently developed computer software package, QCEL, was used to facilitate management and analysis of QC data. The program was used to assess test performance by producing Shewhart-CUSUM control charts which monitored control data for unacceptable fluctuations or trends. QCEL-generated control charts and analyses are presented and discussed. The use of a simple integrated computerised system for storage and analysis of QC control data provided the laboratory with the opportunity to achieve increased confidence in the results of tests performed.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/8828117/