Improvement in coat condition observed in dogs with suspected alopecia X through combined supplementation with nutrients for the coat and skin: A case report

Abstract

Background: Alopecia X is characterized by non-inflammatory hair loss and is commonly observed in dog breeds with double coats and dense undercoats. The exact cause of alopecia X remains unknown, and its complex etiology and diverse responses to treatment make it a challenging condition for veterinarians to manage. Case Description: An 8-year-old Chihuahua (male, unneutered, weight 4.1 kg) with significant hair loss was brought to our clinic. The owner declined to provide a definitive diagnosis; consequently, a diagnosis of suspected alopecia was made based on a physical examination and a series of questions. Horse placenta extract, taurine, and vitamin B complex (B1, B2, B5, and B6) were administered as non-pharmacological therapies. Following a 66-day supplementation regimen, a marked improvement in hair coat coverage was observed, with the back, sides, and abdomen exhibiting near-full-coat coverage. No adverse events were observed during the supplementation period. Following an enhancement in coat condition, supplementation was terminated, and no hair loss was observed during a 76-week follow-up period. Conclusion: The combination of supplements from different categories may be a novel treatment option for owners who wish to pursue non-invasive treatment for alopecia for their dogs. [Open Vet. J. 2025; 15(12.000): 6809-6813]