Peer-reviewed veterinary case report
Cold plasma kills bacteria causing dog skin and ear infections
By Jin, Hee-Jung et al.·Published in Veterinary dermatology·2021·Laboratory of Veterinary Dermatology and The Research Institute for Veterinary Science, South Korea·View original on PubMed →
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Original publication title: In vitro antimicrobial activity of cold atmospheric microwave plasma against bacteria causing canine skin and ear infections.
- Species:
- dog
Plain-English summary
Researchers tested a new treatment called cold atmospheric microwave plasma (CAMP) for bacterial infections in dogs, particularly those causing skin and ear problems. They found that CAMP effectively killed bacteria responsible for these infections, including strains that are resistant to common antibiotics. This treatment could be a promising alternative for dogs suffering from skin infections caused by Staphylococcus pseudintermedius, especially when traditional antibiotics fail. Overall, CAMP showed strong potential in fighting these tough infections in dogs.
People also search for: dog skin infection treatment · cold atmospheric plasma for dogs · antibiotic-resistant dog ear infection
Abstract
BACKGROUND: Cold atmospheric plasma (CAP) is a new generation medical therapeutic option for bacterial infections. CAP causes physical cell wall rupture and DNA damage, therefore making it highly useful in the treatment of various conditions such as skin infections. HYPOTHESIS/OBJECTIVES: The antimicrobial activity of cold atmospheric microwave plasma (CAMP) against major strains in canine skin infections was tested and the difference in antimicrobial activity between the antibiotic-resistant and antibiotic-susceptible strains of Staphylococcus pseudintermedius was evaluated. METHODS AND MATERIALS: American Type Culture Collection (ATCC) strains (Staphylococcus aureus, Pseudomonas aeruginosa and Escherichia coli) and clinical isolates identified as methicillin-resistant S. pseudintermedius (n = 27) and methicillin-susceptible S. pseudintermedius (n = 13) were exposed to CAMP for 10 s, 30 s and 60 s. Afterwards, the bacterial survival rate was confirmed. RESULTS: Gram-negative bacteria (P. aeruginosa and E. coli) were more susceptible than Gram-positive bacteria (S. aureus and S. pseudintermedius) for the same duration of CAMP exposure. Only the Gram-negative bacteria were completely killed after 60 s exposure. In S. pseudintermedius isolates, CAMP exposure had similar antibacterial effects regardless of antibiotic resistance. CONCLUSIONS AND CLINICAL IMPORTANCE: CAMP has sufficient antimicrobial activity against major bacterial strains that cause pyoderma and otitis externa in dogs, and may be an alternative therapeutic option for S. pseudintermedius skin infections, for which antibiotics often are ineffective because of antimicrobial resistance in clinical veterinary medicine.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/34374169/