Peer-reviewed veterinary case report
Honey-based gel kills bacteria and yeast from dog skin infections
By Oliveira, Ana M P et al.·Published in Veterinary dermatology·2018·Faculty of Veterinary Medicine·View original on PubMed →
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Original publication title: In vitro efficacy of a honey-based gel against canine clinical isolates of Staphylococcus pseudintermedius and Malassezia pachydermatis.
- Species:
- dog
Plain-English summary
A group of dogs with skin infections caused by Staphylococcus pseudintermedius and Malassezia pachydermatis were tested with a honey-based gel to see if it could help. The gel was effective at killing these bacteria and yeast, with the best results seen after just four hours of exposure. The honey-based gel worked better than honey alone, suggesting it could be a useful treatment option for dogs suffering from these infections. This could be a promising alternative for pet owners looking for natural treatments for their dogs' skin problems.
People also search for: dog skin infection treatment · honey gel for dog pyoderma · Malassezia in dogs treatment
Abstract
BACKGROUND: Staphylococcus pseudintermedius and Malassezia pachydermatis are important agents in canine pyoderma and otitis. HYPOTHESIS/OBJECTIVES: Determine the in vitro efficacy of a honey-based gel (HBO) against meticillin-susceptible S. pseudintermedius (MSSP), meticillin-resistant S. pseudintermedius (MRSP) and M. pachydermatis, by minimum bactericidal concentration (MBC), minimum fungicidal concentration (MFC) and time-kill assay (TKA). Efficacy of the product's honey component (HO) also was evaluated. METHODS: Sixty S. pseudintermedius and 10 M. pachydermatis canine isolates were selected. All isolates were tested against serial dilutions of an HBO containing 40% HO (40%, 20%, 10%, 5% and 2.5% w/v) and HO alone (undiluted, 40%, 20%, 10%, 5% and 2.5% w/v). Microbroth assay followed by subculture was used to determine MBC and MFC. The same protocol was applied after product exposure to catalase. A well-diffusion assay for S. pseudintermedius was used to generate inhibition zones. A TKA for 10 isolates of S. pseudintermedius and 10 isolates of M. pachydermatis was performed. RESULTS: MBC was 20% w/v (5-20% w/v) for HBO and HO. HBO had lower MBC values when compared to HO (P = 0.003). No statistical difference was observed between MSSP/MRSP isolates (HBO P = 0.757, HO P = 0.743). Only HO was affected by catalase (P = 0.015). MFC for HBO was 10% w/v (5-10% w/v) and 40% w/v for HO (20-≥40% w/v). All isolates were killed after 4 h of exposure. CONCLUSIONS AND CLINICAL IMPORTANCE: Staphylococcus pseudintermedius and M. pachydermatis are susceptible to the HBO and these results can be used for future clinical trials.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/29569291/