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Peer-reviewed veterinary case report

Povidone iodine stops some cat eye infections in lab tests

By Pennington, M R et al.·Published in Veterinary journal (London, England : 1997)·2018·Baker Institute for Animal Health, United States·View original on PubMed

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Original publication title: In vitro efficacy of povidone iodine and hydroxyethyl cellulose, alone and in combination, against common feline ocular pathogens.

Species:
cat

Plain-English summary

A study looked at how well a common antiseptic, povidone-iodine (PVP-I), worked against eye infections in cats caused by viruses and bacteria. It found that PVP-I was effective on its own against some pathogens like feline herpesvirus and Chlamydia, but when combined with hydroxyethyl cellulose (HEC), it worked even better against those same infections. However, it didn't show much effect on feline calicivirus. While these results are promising, more research is needed to ensure safety and effectiveness in real cats before recommending this treatment.

People also search for: cat eye infection treatment · feline herpesvirus symptoms · povidone-iodine for cats

Abstract

Infectious ocular disease, such as conjunctivitis, is common in cats and can be caused by several viruses and bacteria, either as a single infection or as co-infections. In this study, povidone-iodine (PVP-I), alone or compounded with hydroxyethyl cellulose (HEC), was investigated for its efficacy against these pathogens in vitro. Whilst PVP-I alone was effective at inhibiting feline herpesvirus type 1 (FHV-1), Chlamydia felis, and Mycoplasma felis, PVP-I with HEC exerted a synergistic inhibitory effect against FHV-1 and C. felis. In contrast, only minimal inhibition of feline calicivirus was observed. These results demonstrate that PVP-I, alone and in combination with HEC, is effective against some feline ocular pathogens when tested in cell lines in vitro. In vivo studies investigating the systemic safety, ocular tolerance, and clinical efficacy of this combination in cats would be necessary before it could be recommended as a therapy in affected cats.

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Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/30340658/