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Peer-reviewed veterinary case report

In vitro enhancement by CpG ODN of phagocytic activity of rainbow trout head kidney phagocytes against fish pathogen Vibrio ordalii, but not against polystyrene particles.

Journal:
The Journal of veterinary medical science
Year:
2007
Authors:
Nakatani, Masahiro et al.
Affiliation:
Graduate School of Life and Environmental Science · Japan

Abstract

Rainbow trout (Oncorhynchus mykiss) head kidney phagocytes precultured with a synthetic cytidine-phosphate-guanosine (CpG) oligodeoxynucleotide (ODN) displayed significantly higher phagocytic activity against Vibrio ordalii than phagocytes precultured with non-CpG ODN. However, head kidney phagocytes precultured with CpG ODN did not show enhanced phagocytic activity against polystyrene particles.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/18176027/