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Peer-reviewed veterinary case report

In vitro inhibitory activities of sugarcane extract on avian Eimeria sporozoites.

Journal:
International journal for parasitology. Drugs and drug resistance
Year:
2021
Authors:
Daneshmand, Ali et al.
Affiliation:
School of Environmental and Rural Science · United Kingdom
Species:
bird

Abstract

The current in vitro study aimed to investigate the effects of a processed sugarcane extract on the viability of avian Eimeria sporozoites. Treatments were applied to hatched sporozoites: 1) without additives (no-treatment control); 2) with ethanol; 3) with salinomycin; 4) with Polygain&#x2122;. All treatments were incubated in RPMI media containing live sporozoites at 37&#xa0;&#xb0;C for 14&#xa0;h and then the number of viable sporozoites were counted. Compared to the no-treatment control, Polygain&#x2122; decreased (P&#xa0;<&#xa0;0.001) the counts of E. maxima, E. acervulina, E. bruneti, and E. mitis sporozoites to a level similar to salinomycin (P&#xa0;>&#xa0;0.05). In conclusion, Polygain&#x2122; could be a potential candidate as an anticoccidial agent.

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Original publication: https://pubmed.ncbi.nlm.nih.gov/34303187/