Peer-reviewed veterinary case report
Malassezia yeast from dogs with atopic dermatitis in East Asia
By Watanabe, Shion et al.·Published in The Journal of veterinary medical science·2014·Department of Pathobiology, Japan·View original on PubMed →
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Original publication title: In vitro susceptibility of Malassezia pachydermatis isolates from canine skin with atopic dermatitis to ketoconazole and itraconazole in East Asia.
- Species:
- dog
Plain-English summary
A study found that dogs with atopic dermatitis (AD), a skin condition that causes itching and inflammation, had yeast infections caused by Malassezia pachydermatis that were less responsive to common antifungal medications like ketoconazole and itraconazole. The researchers tested samples from dogs in Japan, Korea, and Taiwan and discovered that the yeast from dogs with AD needed higher doses of these medications to be effective compared to those from healthy dogs. This suggests that if your dog has AD and a yeast infection, the usual treatments might not work as well. It's important to discuss this with your veterinarian for the best treatment options.
People also search for: dog atopic dermatitis treatment · Malassezia yeast infection in dogs · antifungal treatment for dog skin problems
Abstract
Topical or oral azole antifungals are commonly used in canine atopic dermatitis (AD), as the lipophilic yeast Malassezia pachydermatis exacerbates canine AD. To examine whether canine AD lesions harbor azole-resistant M. pachydermatis isolates in East Asia, we investigated the in vitro susceptibility of M. pachydermatis isolates to ketoconazole (KTZ) and itraconazole (ITZ) obtained from AD lesions of canines in Japan, Korea and Taiwan. The minimum inhibitory concentrations (MICs) of KTZ and ITZ were measured by the E-test using Sabouraud dextrose agar with 0.5% Tween 40. The MICs of KTZ and ITZ for isolates from canines with AD were significantly higher than the MICs for isolates from healthy canines. Our findings suggested that the clinical isolates from canine AD skin lesions were less susceptible to azoles than those from normal canine skin in East Asia.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/24334863/