Peer-reviewed veterinary case report
Testing Microsporum canis fungus from dogs and cats for drug
By Bagra, Jitendra Kumar et al.·Published in Comparative immunology, microbiology and infectious diseases·2024·Indian Veterinary Research Institute, India·View original on PubMed →
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Original publication title: In vitro virulotyping, antifungal susceptibility testing and DNA fingerprinting of Microsporum canis strains of canine and feline origin.
- Species:
- cat
Plain-English summary
A study found that a common cause of ringworm in pets, called Microsporum canis, was isolated from 70% of sampled cats, especially Persian cats, while only 1.68% of dogs tested positive. The researchers discovered that terbinafine was the most effective antifungal treatment for this infection, while fluconazole was less effective. If your pet shows signs of ringworm, such as hair loss or itchy patches on the skin, it's important to consult your veterinarian about the best treatment options.
People also search for: cat ringworm treatment · dog skin infection antifungal · Persian cat ringworm symptoms
Abstract
Microsporum canis is considered the common dermatophyte agent associated with ringworm in felines and canines. In the present study, we sampled n = 548 felines and canines for the probable isolation of M. canis. The rate of isolation from the cats and dogs was 70.27 % (52/74) and 1.68 % (8/474), respectively and Persian cats were found to be highly susceptible to M. canis infection. The strains were evaluated for their production of phospholipase, lipase, catalase, and hemolysis and their ability to grow at 35 ℃. All the strains were identified as low producers of catalase and n = 17 strains exhibited high thermotolerance ability. Terbinafine was found to be the most effective antifungal drug and fluconazole was the least effective, in vitro. AFLP analysis revealed three genotypes of M. canis with 15 sub-clusters showing ≥ 90 % similarity and 7 sub-clusters exhibiting 100 % similarity. However, the phenotypic characters cannot be attributed based on the AFLP profiles.
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Search related cases →Original publication on PubMed: https://pubmed.ncbi.nlm.nih.gov/38043450/