Peer-reviewed veterinary case report
In vivo study of osteogenerating properties of calcium-phosphate coating on titanium alloy Ti-6Al-4V.
- Journal:
- Bio-medical materials and engineering
- Year:
- 2016
- Authors:
- Gnedenkov, Sergey V et al.
- Affiliation:
- Institute of Chemistry
- Species:
- rodent
Abstract
The method of formation of bioactive calcium-phosphate coating on medical titanium alloy Ti-6Al-4V (3.5-5.3% V; 5.3-6.8% Al; balance -Ti) by plasma electrolytic oxidation (PEO) has been developed. Evaluation of osteogenerating properties of the coating at fractures of the shaft of the femur on Wistar line laboratory rats has been performed. It has been established that the calcium-phosphate PEO coating accelerates osteogenesis and promotes the formation of a pronounced periosteal callus in the fracture area. The presence of calcium phosphates in the PEO coating surface layer significantly accelerates the growth of bone tissue on the titanium surface.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/28234240/