Peer-reviewed veterinary case report
In vivo Treg suppression assays.
- Journal:
- Methods in molecular biology (Clifton, N.J.)
- Year:
- 2011
- Authors:
- Workman, Creg J et al.
- Affiliation:
- Department of Immunology · United States
Abstract
To fully examine the functionality of a regulatory T cell (T(reg)) population, one needs to assess their ability to suppress in a variety of in vivo models. We describe five in vivo models that examine the suppressive capacity of T(regs) upon different target cell types. The advantages and disadvantages of each model including resources, time, and technical expertise required to execute each model are also described.
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Search related cases →Original publication: https://pubmed.ncbi.nlm.nih.gov/21287333/