Peer-reviewed veterinary case report
Inactivated Vaccine for Parrot Herpesvirus Infection (Pacheco's Disease)
- Journal:
- American Journal of Veterinary Research
- Year:
- 1980
- Authors:
- Hitchner, S. B. & Calnek, B. W.
- Affiliation:
- From the Department of Avian and Aquatic Animal Medicine, New York State College of Veterinary Medicine, Cornell University, Ithaca, NY 14853. · United States
- Species:
- bird
Abstract
SUMMARY Four tests of an inactivated emulsified vaccine against a herpesvirus infection (Pacheco's disease) in budgerigars demonstrated that an effective vaccine could be produced with concentrated virus. Virus was propagated in chicken kidney cells, and cells and fluid were harvested 3 to 5 days after inoculation and sonicated. The virus was concentrated 100 × by centrifugation to produce a multiple emulsion vaccine that was protective against im challenge exposure with live virus. The serologic response after vaccination was negligible, and many survivors to virus challenge exposure did not show a positive titer.
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Search related cases →Original publication: https://doi.org/10.2460/ajvr.1980.41.08.1280